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The antigen-antibody immunological reaction is used to be regarded as typical of immunological responses. Antibodies are proteins synthesized by specialized cells called plasma cells, which are formed by lymphocytes (cells from the lymph system) when an antigen, a substance foreign to an organism's body, comes in contact with lymphocytes. Two important manifestations of antigen-antibody immunity are lysis, the rapid physical rupture of antigenic cells and the liberation of their contents into the surrounding medium, and phagocytosis, a process in which antigenic particles are engulfed by and very often digested by macrophages and polymorphs. The process of lysis is executed by a complex and unstable blood constituent known as complement, which will not work unless it is activated by a specific antibody; the process of phagocytosis is greatly facilitated when the particles to be engulfed are coated by a specific antibody directed against them.

What are antibodies?

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The Alaska pipeline starts at the frozen edge of the Arctic Ocean. It stretches southward across the largest and northernmost state in the United States, ending at a remote ice-free seaport village nearly 800 miles from where it begins. It is massive in size and extremely complicated to operate. The steel pipe crosses windswept plains and endless miles of delicate tundra that tops the frozen ground. It weaves through crooked canyons, climbs sheer mountains, plunges over rocky crags, makes its way through thick forests, and passes over or under hundreds of rivers and streams. The pipe is 4 feet in diameter, and up to 2 million barrels (or 84 million gallons) of crude oil can be pumped through it daily. Resting on H-shaped steel racks called "bents", long sections of the pipeline follow a zigzag course high above the frozen earth. Other long sections drop out of sight beneath spongy or rocky ground and return to the surface later on. The pattern of the pipeline's up-and-down route is determined by the often harsh demands of the arctic and subarctic climate, the tortuous lay of the land, and the varied compositions of soil, rock, or permafrost (permanently frozen ground). A little more than half of the pipeline is elevated above the ground. The remainder is buried anywhere from 3 to 12 feet, depending largely upon the type of terrain and the properties of the soil. One of the largest in the world, the pipeline cost approximately $8 billion and is by far the biggest and most expensive construction project ever undertaken by private industry. In fact, no single business could raise that much money, so 8 major oil companies formed a consortium in order to share the costs. Each company controlled oil rights to particular shares of land in the oil fields and paid into the pipeline-construction fund according to the size of its holdings. Today, despite enormous problems of climate, supply shortage, equipment breakdowns, labour disagreements, treacherous terrain, a certain amount of mismanagement, and even theft, the Alaska pipeline has been completed and is operating.

Which of the following were not problems faced while constructing the pipeline?

In the following question, a sentence has been given in Direct/Indirect speech. Out of the four alternatives suggested, select the one, which best express the same sentence in Indirect/Direct speech.

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In the following question the 1st and the last part of the sentence/passage are numbered 1 and 6. The rest of the sentence/ passage is split into four parts and named P, Q, R and S. These four parts are not given in their proper order. Read the sentence/passage and find out which of the four combinations is correct.

1. There was a large gathering at the party.
P. I, too wore a brand new gold jacket.
Q. My black leather shoes were shining.
R. It matched well with my new pair of faded stone washed pants.
S. Everybody had put-on new colourful clothes.
6. They had been polished.

Where was Asia Pacific Economic Cooperation (APEC) 2017 summit held?

Which one of the following events is not correctly matched with the year in which it happened?

The President can dismiss a member of the Council of Ministers

What is the range of frequencies of sound waves audible to human beings?